se dérégler

Contrairement, la production de mélatonine est interrompue avec la lumière et se dérègle avec les changements d'horaires que peut souffrir l'organisme.
On the contrary the production of melatonin is interrupted with light and deregulated with the hourly changes that can undergo the organism.
J'ai passé ma vie à retenir ma respiration de crainte que quelque chose se dérègle.
I've spent my whole life holding my breath afraid that something was gonna spin out of control.
Quand elle s'emballe ou, au contraire, freine son action, c'est tout l'organisme qui se dérègle.
When it gets carried away or, on the contrary, slows down its action, the whole organism goes out of control.
Son rythme se dérègle.
We're losing him!
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