guinea pig

En raison du résultat positif du test GPMT (guinea pig maximisation test), le prescripteur doit tenir compte du risque d’ hypersensibilité lié à la formulation intraveineuse.
Absorption Voriconazole is rapidly and almost completely absorbed following oral administration, with maximum plasma concentrations (Cmax) achieved 1-2 hours after dosing.
L'essai de maximalisation chez le cobaye (GPMT : Guinea Pig Maximisation Test) est un essai avec adjuvant très répandu. Bien qu'il existe plusieurs autres méthodes pour détecter le potentiel de sensibilisation cutanée, le GPMT est l'essai avec adjuvant de prédilection.
Although several other methods can be used to detect the potential of a substance to provoke skin sensitisation reaction, the Gpmt is considered to be the preferred adjuvant technique.
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