en mauvaise condition physique

Les rues pavées de Clovelly sont un coin réputé du Devon auprès des touristes bien qu'elles soient déconseillées aux peureux et aux personnes en mauvaise condition physique : Les rues ici sont si escarpées que les marchandises sont livrées sur des luges.
The cobbled streets of Clovelly are a popular Devon tourist spot, although not for the faint-hearted or unfit: the streets here are so steep that goods are delivered on sledges.
Une diminution de la clairance du fentanyl peut être observée chez les sujets âgés, cachectiques ou en mauvaise condition physique, entraînant une prolongation possible de la demi-vie terminale du fentanyl chez ces patients.
Elderly, cachectic, or debilitated patients may have a reduced clearance of fentanyl and, therefore, the active substance may have a prolonged terminal half-life in these patients.
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