dopa

Levodopa is extensively metabolised to various metabolites, decarboxylation by dopa decarboxylase (DDC) and O-methylation by catechol-O-methyltransferase (COMT) being the most important pathways.
La lévodopa est fortement dégradée en différents métabolites, les principales voies étant la décarboxylation par la dopa décarboxylase (DDC) et l'O-méthylation par la catéchol-O-méthyl transférase (COMT).
Both carbidopa and entacapone block some of the enzymes that are involved in the breakdown of levodopa in the body: carbidopa blocks the enzyme dopa decarboxylase, and entacapone blocks the enzyme catechol-O-methyl transferase (COMT).
La carbidopa et l'entacapone inhibent certaines enzymes qui interviennent dans la dégradation de la lévodopa dans l’ organisme : la carbidopa inhibe la dopa décarboxylase et l'entacapone inhibe la catéchol-O-méthyl transférase (COMT).
Dopamine is a natural catecholamine formed by the decarboxylation of 3,4-dihydroxyphenylalanine (DOPA).
La dopamine est une catécholamine naturelle formée par la décarboxylation de la 3,4-dihydroxyphénylalanine (DOPA).
Sustained or recurrent dysfunction in the phenylalanine-tyrosine-dihydroxy-L-phenylalanine (DOPA) metabolic pathway can result in deficient body protein and neurotransmitter synthesis.
Un dysfonctionnement prolongé ou récidivant de la voie métabolique de la phénylalanine-tyrosine- dihydroxy-L-phénylalanine (DOPA), peut entraîner un déficit de la synthèse des protéines et des neurotransmetteurs corporels.
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