Cushing syndrome

In addition, mitotane induces a state of adrenal insufficiency which leads to the disappearance of Cushing syndrome in patients with secreting adrenal carcinoma and necessitates substitution hormonotherapy.
De plus, le mitotane induit une insuffisance surrénale fonctionnelle qui conduit à la disparition du syndrome de Cushing chez les patients atteints d’ un carcinome corticosurrénalien secrétant et qui nécessite une hormonothérapie substitutive.
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